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Our Science Initiatives

At the forefront of biomedical innovation, our stem cell research spans three key areas:

Disease Research:
We investigate how diseases develop at the cellular level, using stem cells to model conditions, explore disease mechanisms, and develop new therapies.

Developmental Biology:
By studying how stem cells contribute to human development, we gain critical insights into the processes that guide cell growth and differentiation.

Regenerative Medicine:
Harnessing the power of stem cells, we aim to repair or replace damaged tissues and organs—paving the way for transformative treatments.

jmertens@ucsd.edu

Jerome Mertens, PhD

Associate Professor, Neural Aging Laboratory

Our focus is to better understand the interface between the biology of aging and neurodegeneration.

muotri@ucsd.edu

Alysson Muotri, PhD

Professor, Pediatrics

We focus on solving one of life's greatest mysteries: What is it that makes us uniquely human? We study the brain from an evolutionary and developmental perspective, differentiating stem cells to recreate "brain organoids" in the controlled setting of a lab.

ppantham@ucsd.edu

Priyadarshini Pantham, PhD

Assistant Professor, Obstetrics, Gynecology, and Reproductive Sciences

mparast@ucsd.edu

Mana Parast, MD, PhD

Professor, Pathology

We explore the pathophysiology of placenta-based pregnancy disorders, including preeclampsia, fetal growth restriction, and stillbirth. 

mshtrahman@ucsd.edu

Matthew Shtrahman, MD, PhD

Assistant Professor, Neuroscience

We study spatiotemporal patterns of neuronal activity that are generated in the brain. We develop advanced optical techniques for recording neuronal activity in a variety of experimental models to understand how network firing codes for information, is shaped through learning, and becomes altered in diseases of the nervous system.

rsigner@ucsd.edu

Rob Signer, PhD

Associate Professor, Medicine

Our mission is to discover the origins of blood disorders and cancer.

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