Our Science Initiatives
At the forefront of biomedical innovation, our stem cell research spans three key areas:​
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Disease Research:
We investigate how diseases develop at the cellular level, using stem cells to model conditions, explore disease mechanisms, and develop new therapies.
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Developmental Biology:
By studying how stem cells contribute to human development, we gain critical insights into the processes that guide cell growth and differentiation.
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Regenerative Medicine:
Harnessing the power of stem cells, we aim to repair or replace damaged tissues and organs—paving the way for transformative treatments.
Mariko Horii, MD, PhD
Assistant Professor, Pathology
Our lab focuses on understanding the placenta affected pregnancy complications. We use pluripotent stem cells to model the placenta in disease and study the pathophysiology of pregnancy complications at the molecular and cellular level. We are currently studying a variety of diseases with the focus of hypertensive disorder of pregnancy.
Catriona Jamieson, MD, PhD
Professor, Medicine
We study the mutant stem cells and progenitor cells in myeloproliferative neoplasms that can give rise to cancer stem cells. Cancer stem cells may lie low to evade chemotherapy and then activate again later, causing disease progression and resistance to treatment. Our goal is to find more selective, less toxic therapies.
Louise Laurent, MD, PhD
Professor, Obstetrics, Gynecology & Reproductive Sciences
Our lab applies our expertise in human pluripotent stem cell research, and spatial, single-cell, and extracellular omics to understand the molecular mechanisms underlying normal and abnormal human development, in order to improve the health of mothers and babies.
