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Our Science Initiatives

At the forefront of biomedical innovation, our stem cell research spans three key areas:​

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Disease Research:
We investigate how diseases develop at the cellular level, using stem cells to model conditions, explore disease mechanisms, and develop new therapies.

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Developmental Biology:
By studying how stem cells contribute to human development, we gain critical insights into the processes that guide cell growth and differentiation.

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Regenerative Medicine:
Harnessing the power of stem cells, we aim to repair or replace damaged tissues and organs—paving the way for transformative treatments.

dskaufman@ucsd.edu

Dan Kaufman, MD, PhD

Professor, Medicine

We focus on use of human pluripotent stem cells to study basic mechanisms that regulate early human blood cell development and to derive therapeutic mature blood cell populations.

e9kwon@ucsd.edu

Ester Kwon, PhD

Assistant Professor, Bioengineering

Our goal is to use the unique physical, biological, and smart properties of nanoscale materials or "nanomaterials" to create tools, diagnostics, and therapeutics for the central nervous system.

llaurent@health.ucsd.edu

Louise Laurent, MD, PhD

Professor, Obstetrics, Gynecology & Reproductive Sciences

Our lab applies our expertise in human pluripotent stem cell research, and spatial, single-cell, and extracellular omics to understand the molecular mechanisms underlying normal and abnormal human development, in order to improve the health of mothers and babies.

mmarsala@ucsd.edu

Martin Marsala, MD

Professor, Anethesiology

We focus on characterization of patophysiology and treatment of several spinal and brain neurodegenerative disorders.

jmertens@ucsd.edu

Jerome Mertens, PhD

Associate Professor, Neural Aging Laboratory

Our focus is to better understand the interface between the biology of aging and neurodegeneration.

muotri@ucsd.edu

Alysson Muotri, PhD

Professor, Pediatrics

We focus on solving one of life's greatest mysteries: What is it that makes us uniquely human? We study the brain from an evolutionary and developmental perspective, differentiating stem cells to recreate "brain organoids" in the controlled setting of a lab.

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